Gillingham secured a place in the Carling Cup Second Round with an excellent win over the Pilgrims at Priestfield.
Mark Stimson made three changes from Saturday's team with Simon Royce, Kevin Maher and Chris Palmer replacing Julian, Payne, and Bentley.
After a cautious start to proceedings Gillingham created their first decent opening in the 12th minute, Simeon Jackson fed Curtis Weston on the right wing and the midfielder turned defender Jim Paterson before dragging a low effort wide of the near post.
On 20 minutes it was Plymouth's chance to press forward, Alan Judge fed Jamie Mackie in the box but with only Royce to beat he fired straight into the arms of the Gills keeper.
Three minutes later Jackson collected a clearance on the half way line and tore a path through the Argyle defence before lashing a stringing drive over the bar.
In the 28th minute a deep right wing cross found Jim Paterson in space on the left of the area, his cross found the head of Luke Summerfield but Royce was able to gather it comfortably.
Soon after, David McNamee found Rory Fallon with a cross from the right of midfield only to see the big forward head high into the Rainham End.
Weston's 33rd minute persistence allowed Jackson to play in Andy Barcham, the nippy forward looked odds on to score but Larrieu was able to steer the ball to safety at full stretch.
Moments later Steve MacLean chanced his arm from 25 yards and brought a stunning save from Royce to push it wide of the top corner.
Then Gillingham nearly took the lead in the most bizarre circumstances. Chris Palmer's cross was hooked directly at goal by right- back David McNamee fortunately Larrieu pulled off a stunning reflex save to spare his blushes.
Three minutes form half time the Gills broke the deadlock with a cleverly worked goal. Andy Barcham sent Curtis Weston in on goal on the left side of the box and he squared for Simeon Jackson to fire into an empty net.
On the stroke of half time the home side added a second as Plymouth's shell shocked defence failed to deal with Chris Palmer's corner and Andy Barcham climbed highest to head in at the far post.
Early in the second half the Pilgrims pulled a goal back after the Gills conceded a free kick on the edge of the area. Luke Summerfield took responsibility and drove a low shot into the net beyond the diving Royce.
On the hour Gillingham had Royce to thank for stopping a sure equaliser, Jim Paterson bent in a ferocious free-kick from the left and Royce reacted quickly to fist it to safety.
Shortly after Karl Duguid's speculative shot from distance whistled over the cross bar and Jamie Mackie fired into the side netting from close range as the visitors enjoyed a good spell of play.
Seconds after arriving as a second half sub Craig Noone found space and let fly with a shot from the edge of the area that fizzed why of Royce's top hand corner.
As the minutes ticked by Plymouth threw caution to the wind and were unlucky again after 82 minutes, sub Barnes found Duguid on the right of the box but his low drive was well held by Royce.
At the other end Gillingham could have booked their place in Round Two as Mark McCammon pounced on a mistake at the back only to see his low finish stick under Larrieu and deflect to safety.
In added time Plymouth missed an unforgiveable chance as Fallon sent Mackie through on goal but the striker pulled wide of the near post with Royce beaten.
Find out the Gills next opponents when the draw for Round Two of the Carling Cup takes place at 10.00pm on Wednesday 12th of August on Sky Sports News.
Attendance: 3122 (321 away fans)
Gillingham: Simon Royce, Barry Fuller, Garry Richards, Josh Gowling, John Nutter, Chris Palmer (79 Luke Rooney), Adam Miller, Kevin Maher (72 Mark McCammon), Curtis Weston, Andy Barcham, Simeon Jackson.
Subs: Alan Julian, Jacob Erskine, Tom Wynter, Rashid Yussuff, Jack Payne.
Plymouth Argyle: Romain Larrieu, Marcel Seip, Gary Sawyer, Jim Paterson, Jamie Mackie, Rory Fallon, Karl Duguid, Steve MacLean (73 Craig Noone), David McNamee, Luke Summerfield (80 Ashley Barnes), Alan Judge (73 Chris Clark)
Subs: Kyle Letheren, Kari Arnason, Joe Mason, Damien McCrory.